Article

Neutrophil remodeling is associated with human meibomian gland dysfunction and enables IFN-γ- and PAD4-dependent gland obstruction in mice

2026-08-24

Abstract excerpt

<h4>ABSTRACT</h4> Meibomian gland dysfunction (MGD), a disorder of the eyelid’s modified sebaceous glands, is the leading cause of dry eye disease and ocular surface morbidity, yet the immune mechanisms driving gland obstruction remain poorly defined. In a cross-sectional study of 66 patients with ocular surface inflammation, we used meibography and spectral flow cytometry of tear washes to identify a disease-ass...

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Literature Corpus work: 8d95ad0c-f73a-5db3-8790-1d945523b6ff
DOI: 10.64898/2026.08.19.744915

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