Article

Pericellular oxygen dynamics in human cardiac fibroblasts and iPSC-cardiomyocytes in high-throughput plates: insights from experiments and modeling

2025-02-24

Abstract excerpt

<h4>ABSTRACT</h4> Adequate oxygen supply is crucial for proper cellular function. The emergence of high-throughput (HT) expansion of human stem-cell-derived cells and HT in vitro cellular assays for drug testing necessitate monitoring and understanding of the oxygenation conditions, yet virtually no data exists for such settings. For metabolically active cells like cardiomyocytes, variations in oxygenation may s...

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Literature Corpus work: 65c7da17-31c3-54c5-93d5-4c66061a605d
DOI: 10.1101/2025.02.19.639086

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