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Efficient and reproducible generation of human iPSC-derived cardiomyocytes using a stirred bioreactor

2024-02-28

Abstract excerpt

In the last decade human iPSC-derived cardiomyocytes (hiPSC-CMs) proved to be valuable for cardiac disease modeling and cardiac regeneration, yet challenges with scale, quality, inter-batch consistency, and cryopreservation remain, reducing experimental reproducibility and limiting clinical translation. Here, we report a robust cardiac differentiation protocol that uses Wnt modulation and a stirred suspension bior...

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Literature Corpus work
d2983261-1c7b-50c9-96e2-5f1723dfabe1
DOI
10.1101/2024.02.24.581789
Open publication

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Efficient and reproducible generation of human iPSC-derived cardiomyocytes using a stirred bioreactorDOI 10.1101/2024.02.24.581789
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