Oxygen in the cultivation of stem cells.

Abstract excerpt

Cultivation of stem cells, like all cells in culture, is performed under conditions that cannot and do not replicate normal physiologic conditions. For example, direct exposure of cultured monolayer cells to serum contents is normally prevented in vivo by the vasculature. The heterogeneity of cells and signals between different cell types in an organ is certainly not captured when a single cell type is grown and...

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