Article

Comprehensive promotion of iPSC-CM maturation by integrating metabolic medium, nanopatterning, and electrostimulation

2024-04-10

Abstract excerpt

<title>Abstract</title> <p>The immaturity of human induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) is a major limitation for their use in drug screening to identify pro-arrhythmogenic or cardiotoxic molecules, thus hindering their potential role in guiding personalised drug selection for patients. Here, we demonstrate an approach that combines lipid-enriched maturation medium, nanopatterning of cu...

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Literature Corpus work: 092acc6e-6282-5751-8f4d-48cb6eeb4aac
DOI: 10.21203/rs.3.rs-3973784/v1

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