Article

Human Plasma-Like Medium Promotes Maturation of Human Pluripotent Stem Cell-Derived Cardiomyocytes

2025-04-26

Abstract excerpt

Maturing human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) in vitro is critical for advancing drug discovery and cardiotoxicity screening applications of these cells. However, the metabolic compositions of basal media used for hPSC-CM culture typically offer limited relevance to human cardiac physiology. Here, we examined how culture in Human Plasma-Like Medium (HPLM) versus conventional basal media a...

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Literature Corpus work: a76b0c6d-4ab0-58c6-a2fe-0cada6d8711d
DOI: 10.1101/2025.04.24.650456

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