Article

Gene Age Gap Estimate (GAGE) for major depressive disorder: a penalized biological age model using gene expression

2024-09-04

Abstract excerpt

Recent associations between Major Depressive Disorder (MDD) and measures of premature aging suggest accelerated biological aging as a potential biomarker for MDD susceptibility or MDD as a risk factor for age-related diseases. Residuals or “gaps” between the predicted biological age and chronological age have been used for statistical inference, such as testing whether an increased age gap is associated with a giv...

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Literature Corpus work: 65c79c91-03c8-5089-a668-1e3359424330
DOI: 10.1101/2024.09.03.610913

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