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Lifestyle, Early-life, and Genetic Health Risk Factors Underlying the Brain Age Gap: A Mega-Analysis Across 3,934 Individuals from the ENIGMA MDD Consortium

2025-05-11

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Large-scale studies show that adults with major depressive disorder (MDD) generally have a higher imaging-predicted age relative to their chronological age (i.e., positive brain age gap) compared to controls, though considerable within-group variation exists. This study examines lifestyle, early-life, and genetic health risk factors contributing to the brain age gap. Identif...

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Literature Corpus work: bd6205cb-5b97-5994-8990-6fbe60947996
DOI: 10.1101/2025.05.09.653064

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Lifestyle, Early-life, and Genetic Health Risk Factors Underlying the Brain Age Gap: A Mega-Analysis Across 3,934 Individuals from the ENIGMA MDD ConsortiumDOI 10.1101/2025.05.09.653064Read

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