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Article

Anticipated brain molecular aging in major depression.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry - 1 May 2013

Douillard-Guilloux Gaëlle, Guilloux Jean-Philippe, Lewis David A, Sibille Etienne

Abstract excerpt

OBJECTIVES: Brain molecular aging, the pervasive and consistent transcriptome changes associated with normal brain aging, appears to overlap with disease pathways and may be anticipated in neurodegenerative and neuropsychiatric diseases, including major depressive disorder (MDD). Here, we characterize the global interaction of MDD-related gene changes with age, starting from our previous report of downregulated...

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Identifiers

PMID: 23570888
DOI: 10.1016/j.jagp.2013.01.040
PMCID: PMC3615087

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BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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