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Article

The age-by-disease interaction hypothesis of late-life depression.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry - 1 May 2013

McKinney Brandon Chad, Sibille Etienne

Abstract excerpt

The phenomenologic diagnosis of depression is successful in increasing diagnostic reliability, but it is a classification scheme without biologic bases. One subtype of depression for which evidence suggests a unique biologic basis is late-life depression (LLD), with first onset of symptoms after the age of 65. LLD is common and poses a significant burden on affected individuals, caretakers, and society. The...

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Identifiers

PMID: 23570886
DOI: 10.1016/j.jagp.2013.01.053
PMCID: PMC3549303

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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