Article
Whole Blood Gene Expression Associated With Clinical Biological Age.
The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Jan 2019
Lin Honghuang, Lunetta Kathryn L, Zhao Qiang, Mandaviya Pooja R, Rong Jian, Benjamin Emelia J, Joehanes Roby, Levy Daniel, van Meurs Joyce B J, Larson Martin G, Murabito Joanne M
Abstract excerpt
Background: Biologic age may better reflect an individual's rate of aging than chronologic age. Methods: We conducted a transcriptome-wide association study with biologic age estimated with clinical biomarkers, which included: systolic blood pressure, forced expiratory volume at 1 second (FEV1), total cholesterol, fasting glucose, C-reactive protein, and serum creatinine. We assessed the association between the...
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