Article
Genetic markers for depressive disorders with earlier age at onset.
Progress in neuro-psychopharmacology & biological psychiatry - 8 Jun 2021
Kang Hee-Ju, Kim Ki-Tae, Park Yoomi, Yoo Kyung-Hun, Kim Ju-Wan, Lee Ju-Yeon, Kim Sung-Wan, Shin Il-Seon, Kim Ju Han, Kim Jae-Min
Abstract excerpt
Age at onset has been considered a potential indicator of underlying genetic risk in depression research. However, the variants associated with earlier age at onset of depressive disorder have not been elucidated. To evaluate the genetic architecture of depression onset, whole-exome sequencing of samples from 1000 patients with depressive disorder was performed. Cox proportional hazard models with false discovery...
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