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Apolipoprotein E Genotype and Sex Risk Factors for Alzheimer Disease

28 Aug 2017

Abstract excerpt

Importance: It is unclear whether female carriers of the apolipoprotein E (APOE) ε4 allele are at greater risk of developing Alzheimer disease (AD) than men, and the sex-dependent association of mild cognitive impairment (MCI) and APOE has not been established. Objective: To determine how sex and APOE genotype affect the risks for developing MCI and AD. Data Sources: Twenty-seven independent research studies in...

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Alzheimer's disease research and treatments
Dementia and Cognitive Impairment Research
Schizophrenia research and treatment

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28846757
DOI: 10.1001/jamaneurol.2017.2188

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