Article
Investigation of sex differences in mutation carriers of the Dominantly Inherited Alzheimer Network.
Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Jan 2024
Wagemann Olivia, Li Yan, Hassenstab Jason, Aschenbrenner Andrew J, McKay Nicole S, Gordon Brian A, Benzinger Tammie L S, Xiong Chengjie, Cruchaga Carlos, Renton Alan E, Perrin Richard J, Berman Sarah B, Chhatwal Jasmeer P, Farlow Martin R, Day Gregory S, Ikeuchi Takeshi, Jucker Mathias, Lopera Francisco, Mori Hiroshi, Noble James M, Sánchez-Valle Raquel, Schofield Peter R, Morris John C, Daniels Alisha, Levin Johannes, Bateman Randall J, McDade Eric, Llibre-Guerra Jorge J
Abstract excerpt
INTRODUCTION: Studies suggest distinct differences in the development, presentation, progression, and response to treatment of Alzheimer's disease (AD) between females and males. We investigated sex differences in cognition, neuroimaging, and fluid biomarkers in dominantly inherited AD (DIAD). METHODS: Three hundred twenty-five mutation carriers (55% female) and one hundred eighty-six non-carriers (58% female) of...
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