Sex-Specific Association of Apolipoprotein E With Cerebrospinal Fluid Levels of Tau.

doi:10.1001/jamaneurol.2018.0821

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Article

Sex-Specific Association of Apolipoprotein E With Cerebrospinal Fluid Levels of Tau.

JAMA neurology - 1 Aug 2018

Hohman Timothy J, Dumitrescu Logan, Barnes Lisa L, Thambisetty Madhav, Beecham Gary, Kunkle Brian, Gifford Katherine A, Bush William S, Chibnik Lori B, Mukherjee Shubhabrata, De Jager Philip L, Kukull Walter, Crane Paul K, Resnick Susan M, Keene C Dirk, Montine Thomas J, Schellenberg Gerard D, Haines Jonathan L, Zetterberg Henrik, Blennow Kaj, Larson Eric B, Johnson Sterling C, Albert Marilyn, Bennett David A, Schneider Julie A, Jefferson Angela L

Abstract excerpt

Importance: The strongest genetic risk factor for Alzheimer disease (AD), the apolipoprotein E (APOE) gene, has a stronger association among women compared with men. Yet limited work has evaluated the association between APOE alleles and markers of AD neuropathology in a sex-specific manner. Objective: To evaluate sex differences in the association between APOE and markers of AD neuropathology measured in...

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Identifiers

PMID: 29801024
DOI: 10.1001/jamaneurol.2018.0821
PMCID: PMC6142927

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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