Article

Tunable protein synthesis by transcript isoforms in human cells

2015-12-23

Abstract excerpt

Eukaryotic genes generate multiple mRNA transcript isoforms though alternative transcription, splicing, and polyadenylation. However, the relationship between human transcript diversity and protein production is complex as each isoform can be translated differently. We fractionated a polysome profile and reconstructed transcript isoforms from each fraction, which we term Transcript Isoforms in Polysomes sequencing...

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Literature Corpus work: 65494d42-48e9-5c75-aa11-8804fa96476a
DOI: 10.1101/035188

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