Article

An integrated landscape of mRNA and protein isoforms

2025-04-19

Abstract excerpt

<h4>Summary</h4> Alternative splicing and proteolytic processing expand the functional diversity of the human proteome by generating distinct protein isoforms from a single gene. However, the extent to which transcript isoforms give rise to distinct protein products remains unclear, in part due to technical limitations in proteomic workflows. Here, we combine full-length mRNA sequencing with SDS-PAGE-based protei...

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Literature Corpus work: bd8a0545-aa20-5165-8812-ff701a838664
DOI: 10.1101/2025.04.16.648713

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