Article

Identification of a large class of cancer–germline microproteins as a source of immunotherapeutic targets

2026-05-20

Abstract excerpt

Classical cancer germline-antigens (CGAs) are proteins that are expressed in the male germinal line but not in somatic tissues, and that can also become expressed in tumors. However, the vast majority of testis-specific transcripts are long non-coding RNAs (lncRNAs) rather than protein-coding genes. Since recent studies have shown that many lncRNAs contain non-canonical open reading frames (ncORFs) that are transl...

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Literature Corpus work: 653595e4-dfc2-5206-a390-19eefb7db9c8
DOI: 10.64898/2026.05.18.725836

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