Article

Systematic identification of cancer-specific MHC-binding peptides with RAVEN

2017-09-24

Abstract excerpt

<h4>ABSTRACT</h4> Immunotherapy can revolutionize anti-cancer therapy if specific targets are available. Recurrent somatic mutations in the exome can create highly specific neo-antigens. However, especially pediatric cancers are oligo-mutated and hardly exhibit recurrent neo-antigens. Yet, immunogenic peptides encoded by cancer-specific genes (CSGs), which are virtually not expressed in normal tissues, may enable...

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Literature Corpus work: 3ea08e12-e8e1-5f56-9e65-432970f8787d
DOI: 10.1101/193276

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