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Proteogenomic analysis reveals RNA as a source for tumor-agnostic neoantigen identification

2 Aug 2023

Abstract excerpt

Systemic pan-tumor analyses may reveal the significance of common features implicated in cancer immunogenicity and patient survival. Here, we provide a comprehensive multi-omics data set for 32 patients across 25 tumor types for proteogenomic-based discovery of neoantigens. By using an optimized computational approach, we discover a large number of tumor-specific and tumor-associated antigens. To create a...

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PMID: 37532709
DOI: 10.1038/s41467-023-39570-7

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