Article

Massive expression of germ cell specific genes is a hallmark of cancer and a potential target for novel treatment development

2017-09-28

Abstract excerpt

Cancer cells have been found to frequently express genes that are normally restricted to the testis, often referred to as cancer/testis (CT) antigens or genes 1, 2 . Because germ cell specific antigens are not recognized as “self” by the innate immune system 3 , CT-genes have previously been suggested as ideal candidate targets for cancer therapy 4 . The use of CT- genes in cancer therapy has thus far been unsu...

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Literature Corpus work: 2dc2e0ef-f1f5-529f-82b6-1a5de8862c3a
DOI: 10.1101/195305

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