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Article

The PRAME family of cancer testis antigens is essential for germline development and gametogenesis

19 Apr 2021

Abstract excerpt

Preferentially expressed antigen in melanoma (PRAME) belongs to a group of cancer/testis antigens that are predominately expressed in the testis and a variety of tumors, and are involved in immunity and reproduction. Much of the attention on PRAME has centered on cancer biology as PRAME is a prognostic biomarker for a wide range of cancers and a potential immunotherapeutic target. Less information is available...

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PMID: 33880503
DOI: 10.1093/biolre/ioab074

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