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A proteome-wide association study of cardiovascular diseases in 640,000 participants of multiple ancestries

2026-08-06

Abstract excerpt

Proteomics holds great promise for identifying potentially druggable effectors of common diseases, yet its application at population-scale across diverse ancestries, remains challenging. Here, we developed genetic imputation models for 2,594 plasma proteins using proteomic and genetic data from 54,219 UK Biobank participants, validating their performance across multiple ancestry groups and in an independent cohort...

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Literature Corpus work
64c6b069-b7e5-57c2-9baf-145c155b9e22
DOI
10.64898/2026.08.04.26359685
Open publication

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A proteome-wide association study of cardiovascular diseases in 640,000 participants of multiple ancestriesDOI 10.64898/2026.08.04.26359685
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