Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Integrative proteomic analyses across common cardiac diseases yield mechanistic insights and enhanced prediction

21 Nov 2024

Abstract excerpt

Cardiac diseases represent common highly morbid conditions for which molecular mechanisms remain incompletely understood. Here we report the analysis of 1,459 protein measurements in 44,313 UK Biobank participants to characterize the circulating proteome associated with incident coronary artery disease, heart failure, atrial fibrillation and aortic stenosis. Multivariable-adjusted Cox regression identified 820...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bioinformatics and Genomic Networks
Share to Genetic Associations and Epidemiology
Share to Lipoproteins and Cardiovascular Health

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39572695
DOI: 10.1038/s44161-024-00567-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Integrative proteomic analyses across common cardiac diseases yield mechanistic insights and enhanced predictionPMID 39572695Read ↗

Proteome-wide Mendelian randomization identifies candidate causal proteins for cardiovascular diseasesSemantic proximity Read ↗

A proteome-wide association study of cardiovascular diseases in 640,000 participants of multiple ancestriesSemantic proximity Read ↗

Large-scale identification of protein biomarkers and therapeutic targets in heart and brain disease.Semantic proximity Read ↗

Blood plasma proteome-wide association study implicates novel proteins in the pathogenesis of multiple cardiovascular diseases.Semantic proximity Read ↗

Plasma proteomic architecture of incident valvular heart disease in the UK Biobank: discovery, genetic prioritization, and exploratory risk discriminationSemantic proximity Read ↗

Measured and genetically predicted protein levels and cardiovascular diseases in UK Biobank and China Kadoorie Biobank.Semantic proximity Read ↗

Circulating cardiovascular proteomic associations with genetics and diseaseSemantic proximity Read ↗

Plasma proteins and onset of atherosclerosis: Integrating human plasma proteogenomics, transcriptomics and in vivo evidenceSemantic proximity Read ↗

Circulating causal protein networks linked to future risk of myocardial infarctionSemantic proximity Read ↗

Cross-population proteome-wide mendelian randomization study identifies likely causal proteins for cardiovascular diseases.Semantic proximity Read ↗

Proteomic analysis of 92 circulating proteins and their effects in cardiometabolic diseasesSemantic proximity Read ↗

Causal Effect of Multicohort Circulating Proteome on the Risk of Aortic Aneurysm: A Mendelian Randomization Study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.