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Article

SELECTION OF ANTI-NUCLEAR ANTIGEN (ANA) REACTIVE B CELLS IN SYSTEMIC LUPUS ERYTHEMATOSUS

2025-01-13

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objective</h4> Autoreactive B cells that recognize nuclear antigens are normally present in healthy individuals and patients with systemic lupus erythematosus (SLE), yet their activation and the production of IgG autoantibodies is a hallmark of SLE. The selection process and regulation of these cells in patients with SLE has not been completely understood. To gain insights into tolerance ch...

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Literature Corpus work
6476513a-e0b6-5893-b6cc-cb620821f5d8
DOI
10.1101/2025.01.08.631945
Open publication

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