Article

SLE Antibody-Secreting Cells Are Characterized by Enhanced Peripheral Maturation and Survival Programs

2023-06-27

Abstract excerpt

<title>Abstract</title> <p>Systemic Lupus Erythematosus (SLE) is an autoimmune disease characterized by multiple autoantibodies, some of which are present in high titers in a sustained, B cell-independent fashion consistent with their generation from long-lived plasma cells (LLPC). Active SLE displays high numbers of circulating antibody-secreting cells (ASC). Understanding the mechanisms of generation and surviv...

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Literature Corpus work: bda4a18a-145f-510e-a955-6ce70febbda8
DOI: 10.21203/rs.3.rs-3016327/v1

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