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B cell receptor repertoire abnormalities in autoimmune disease

30 Jan 2024

Abstract excerpt

B cells play a crucial role in the immune response and contribute to various autoimmune diseases. Recent studies have revealed abnormalities in the B cell receptor (BCR) repertoire of patients with autoimmune diseases, with distinct features observed among different diseases and B cell subsets. Classically, BCR repertoire was used as an identifier of distinct antigen-specific clonotypes, but the recent...

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PMID: 38361948
DOI: 10.3389/fimmu.2024.1326823

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