Transcriptome and IgH Repertoire Analyses Show That CD11chi B Cells Are a Distinct Population With Similarity to B Cells Arising in Autoimmunity and Infection

Abstract excerpt

A distinct B cell population marked by elevated CD11c expression is found in patients with systemic lupus erythematosus (SLE). Cells with a similar phenotype have been described during chronic infection, but variable gating strategies and nomenclature have led to uncertainty of their relationship to each other. We isolated CD11chi cells from peripheral blood and characterized them using transcriptome and IgH...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Immune Cell Function and Interaction
• Share to Monoclonal and Polyclonal Antibodies Research
• Share to T-cell and B-cell Immunology