Article

Multiplexed 3D atlas of state transitions and immune interactions in colorectal cancer

2021-04-02

Abstract excerpt

<h4>SUMMARY</h4> Advanced solid cancers are complex assemblies of tumor, immune, and stromal cells characterized by high intratumoral variation. We use highly multiplexed tissue imaging, 3D reconstruction, spatial statistics, and machine learning to identify cell types and states underlying morphological features of known diagnostic and prognostic significance in colorectal cancer. Quantitation of these features...

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Literature Corpus work: 6471bf1a-cbcb-5077-801d-f13af2c980a4
DOI: 10.1101/2021.03.31.437984

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