Article

High-Resolution Spatial Proteomics Characterises Colorectal Cancer Consensus Molecular Subtypes

2025-05-10

Abstract excerpt

<h4>Background</h4> Identification of the consensus molecular subtypes (CMS) opened significant potential for understanding the tumor biology and intertumoral heterogeneity of colorectal cancer (CRC). However, molecular subtyping in CRC traditionally relies on bulk transcriptomics, therefore, lacks spatial and single-cell level aspect. <h4>Methods</h4> We constructed tissue microarrays using tumor cores from 222...

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Literature Corpus work: a7b3671f-745f-590b-892d-a901f9a16194
DOI: 10.1101/2025.05.07.652478

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