Article

High-resolution molecular atlas of a lung tumor in 3D

2023-05-10

Abstract excerpt

<h4>ABSTRACT</h4> Cells live and interact in three-dimensional (3D) cellular neighborhoods. However, histology and spatial omics methods mostly focus on 2D tissue sections. Here we present a 3D spatial atlas of a routine clinical sample, an aggressive human lung carcinoma, by combining in situ quantification of 960 cancer-related genes across ∼340,000 cells with measurements of tissue-mechanical components. 3D c...

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Literature Corpus work: 837a6208-50f0-5b07-a1b9-b52ab12af811
DOI: 10.1101/2023.05.10.539644

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