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Article

A short ERAP2 that binds IRAP is expressed in macrophages independently from gene variation

2022-03-07

Abstract excerpt

The M1 zinc metalloproteases ERAP1, ERAP2 and IRAP play a role in HLA-I antigen presentation by refining the peptidome either in the ER (ERAP1 and ERAP2) or in the endosomes (IRAP). They have been also entrusted with other, although less defined, functions such as the regulation of the angiotensin system and blood pressure. In humans, ERAP1 and IRAP are commonly expressed. ERAP2 instead has evolved under balancing...

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Identifiers and source

Literature Corpus work
63fe7fc1-b098-592d-9ecc-dc2e3f528ea8
DOI
10.1101/2022.03.07.483178
Open publication

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A short ERAP2 that binds IRAP is expressed in macrophages independently from gene variationDOI 10.1101/2022.03.07.483178
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