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Article

The Impact of the 'Mis-Peptidome' on HLA Class I-Mediated Diseases: Contribution of ERAP1 and ERAP2 and Effects on the Immune Response.

International journal of molecular sciences - 17 Dec 2020

Tedeschi Valentina, Paldino Giorgia, Paladini Fabiana, Mattorre Benedetta, Tuosto Loretta, Sorrentino Rosa, Fiorillo Maria Teresa

Abstract excerpt

The strong association with the Major Histocompatibility Complex (MHC) class I genes represents a shared trait for a group of autoimmune/autoinflammatory disorders having in common immunopathogenetic basis as well as clinical features. Accordingly, the main risk factors for Ankylosing Spondylitis (AS), prototype of the Spondyloarthropathies (SpA), the Behçet's disease (BD), the Psoriasis (Ps) and the Birdshot...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to CD8-Positive T-Lymphocytes

Share to Genes, MHC Class I

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Share to Spondylitis, Ankylosing

Source

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Identifiers

PMID: 33348540
DOI: 10.3390/ijms21249608
PMCID: PMC7765998

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The Impact of the 'Mis-Peptidome' on HLA Class I-Mediated Diseases: Contribution of ERAP1 and ERAP2 and Effects on the Immune Response.PMID 33348540Read ↗

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