Article

Chromatin co-accessibility is highly structured, spans entire chromosomes, and mediates long range regulatory genetic effects

2019-04-09

Abstract excerpt

Chromatin accessibility identifies active regions of the genome, often at transcription factor (TF) binding sites, enhancers, and promoters, and contains regulatory genetic variation. Functionally related accessible sites have been reported to be co-accessible; however, the prevalence and range of co-accessibility is unknown. We perform ATAC-seq in induced pluripotent stem cells from 134 individuals and integrate...

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Literature Corpus work: 63efbec6-da26-5170-88a7-61fc17d1029c
DOI: 10.1101/604371

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