Article

Integrative Comparison of GeneHancer and Single-Cell Co-accessibility Reveals Active Enhancer–Gene Interactions

2026-01-23

Abstract excerpt

Linking enhancers to their target genes remains challenging due to the context-independent nature of curated annotations and the noise inherent in data-driven predictions. GeneHancer provides a comprehensive catalogue of enhancer–gene associations, but many elements are inactive in specific biological settings. Conversely, co-accessibility inferred from single-cell chromatin accessibility data captures sample-spec...

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Literature Corpus work: 6c00cd6d-f65c-5cbb-9dcb-5c938600c567
DOI: 10.64898/2026.01.23.701222

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