Article

<i>DifferentialRegulation</i> : a Bayesian hierarchical approach to identify differentially regulated genes

2023-08-17

Abstract excerpt

<h4>Summary</h4> <h4>Motivation</h4> Although transcriptomics data is typically used to analyse mature spliced mRNA, recent attention has focused on jointly investigating spliced and unspliced (or precursor-) mRNA, which can be used to study gene regulation and changes in gene expression production. Nonetheless, most methods for spliced/unspliced inference (such as RNA velocity tools) focus on individual samples...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9bc64357-ed6c-5bdd-8a8c-e19b37e83932
DOI: 10.1101/2023.08.17.553679

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

<i>DifferentialRegulation</i> : a Bayesian hierarchical approach to identify differentially regulated genesDOI 10.1101/2023.08.17.553679Read

Robust identification of regulatory variants (eQTLs) using a differential expression framework developed for RNA-sequencingSemantic proximity Read

Expression and Splicing Mediate Distinct Biological SignalsSemantic proximity Read

RNA sequencing depth guidelines for the study of alternative splicingSemantic proximity Read

<i>satuRn:</i> Scalable Analysis of differential Transcript Usage for bulk and single-cell RNA-sequencing applicationsSemantic proximity Read

Selecting differential splicing methods: Practical considerationsSemantic proximity Read

An RNA-seq quantification method for analysis of transcriptional aberrationsSemantic proximity Read

Selecting differential splicing methods: Practical considerations for short-read RNA sequencingSemantic proximity Read

Latent variable modelling and variational inference for scRNA-seq differential expression analysisSemantic proximity Read

Comprehensive and scalable quantification of splicing differences with MntJULiPSemantic proximity Read

Characterizing the landscape of gene expression variance in humansSemantic proximity Read

Cell-type-specific alternative polyadenylation (APA) genes reveal the function of dynamic APA in complex tissuesSemantic proximity Read

Transcriptome sequencing suggests that pre-mRNA splicing counteracts widespread intronic cleavage and polyadenylationSemantic proximity Read