Article

Naked mole-rat acid-sensing ion channel 3 forms nonfunctional homomers, but functional heteromers

2017-07-21

Abstract excerpt

<h4>ABSTRACT</h4> Acid-sensing ion channels (ASICs) form both homotrimeric and heterotrimeric ion channels that are activated by extracellular protons and are involved in a wide range of physiological and pathophysiological processes, including pain and anxiety. ASIC proteins can form both homotrimeric and heterotrimeric ion channels. The ASIC3 subunit has been shown to be of particular importance in the peripher...

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Literature Corpus work: 63947678-5761-56ac-a6f5-a137425a70a3
DOI: 10.1101/166272

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