Article

Silencing <i>XIST</i> on the future active X: Searching human and bovine preimplantation embryos for the repressor

2021-10-07

Abstract excerpt

<h4>ABSTRACT</h4> X inactivation is the means of equalizing the dosage of X chromosomal genes in male and female eutherian mammals, so that only one X is active in each cell. The XIST locus ( in cis ) on each additional X chromosome initiates the transcriptional silencing of that chromosome, making it an inactive X. How the active X in both males and females is protected from inactivation by its own XIST loc...

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Literature Corpus work: 35bf5920-d3c4-5e82-8e65-db6aac2c9f91
DOI: 10.1101/2021.10.05.463256

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