Article

Spatiotemporal profiling reveals the impact of caloric restriction on mammalian brain aging

2025-05-08

Abstract excerpt

<h4>Summary</h4> Aging induces functional declines in the mammalian brain, increasing its vulnerability to cognitive impairments and neurodegenerative disorders. Among various interventions to slow the aging process, caloric restriction (CR) has consistently demonstrated the ability to extend lifespan and enhance brain function across different species. Yet the precise molecular and cellular mechanisms by which C...

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Literature Corpus work: 63077a3d-7866-50c6-bf73-90ac86e3f785
DOI: 10.1101/2025.05.04.652093

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