Article

Heterochronic parabiosis reprograms the mouse brain transcriptome by shifting aging signatures in multiple cell types

2022-01-28

Abstract excerpt

Aging is a complex process involving transcriptomic changes associated with deterioration across multiple tissues and organs, including the brain. Recent studies using heterochronic parabiosis have shown that various aspects of aging-associated decline are modifiable or even reversible. To better understand how this occurs, we performed single-cell transcriptomic profiling of young and old mouse brains following p...

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Literature Corpus work: b6d6983a-7169-54bc-bc43-077c08e6876e
DOI: 10.1101/2022.01.27.477911

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