Article

Spatially resolved multiomics on the neuronal effects induced by spaceflight

2023-05-31

Abstract excerpt

<title>Abstract</title> <p>Impairment of the central nervous system (CNS) functions in astronauts is a major health risk for long-duration space missions. Here, for the first time, we combine single-cell multiomics (transcriptomics and chromatin accessibility) and spatial transcriptomics analyses to discover spaceflight-mediated changes in the mouse brain. By comparing ground control and spaceflight animals, we f...

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Literature Corpus work: 0e9145d1-2625-505c-9a52-a8da8a5f9f7a
DOI: 10.21203/rs.3.rs-2865086/v1

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