Gene expression atlas of the mouse central nervous system: impact and interactions of age, energy intake and gender

Abstract excerpt

BACKGROUND: The structural and functional complexity of the mammalian central nervous system (CNS) is organized and modified by complicated molecular signaling processes that are poorly understood. RESULTS: We measured transcripts of 16,896 genes in 5 CNS regions from cohorts of young, middle-aged and old male and female mice that had been maintained on either a control diet or a low energy diet known to retard...

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