Spatiotemporal transcriptomic maps of mouse intracerebral hemorrhage at single-cell resolution

Abstract excerpt

<h4>Summary</h4> Intracerebral hemorrhage (ICH) is a severe and widespread disease that results in high mortality and morbidity. Despite significant advances made in clinical and preclinical research, the prognosis of ICH remains poor due to an incomplete understanding of the complex pathological responses. To address this challenge, we generated single-cell resolution spatiotemporal transcriptomic maps of mouse...

Topics

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• Barrier Structure and Function Studies
• Immune Response and Inflammation
• Intracranial Aneurysms: Treatment and Complications
• Neonatal Respiratory Health Research
• Neuroinflammation and Neurodegeneration Mechanisms
• Single-cell and spatial transcriptomics

Identifiers and source

Literature Corpus work

bd8e79e4-5aa4-5c8d-93ac-4628f6825e97

DOI

10.1101/2024.05.23.595245