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terminator hinders the higher erythropoietin production achieved through Matrix Attachment Region in CHO-K1 cells

2025-06-30

Abstract excerpt

<title>Abstract</title> <p>Strategies to achieve substantial yield from Chinese hamster ovarian (CHO) cell factories remain crucial in the biopharmaceutical industry. Chromosome remodeling, mRNA 3' end extension diversity, mRNA maturation, and the utilization of upstream and downstream DNA elements have been shown to impact the production of recombinant proteins significantly. In this study, we employed the human...

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Literature Corpus work: 615d3a00-9598-55c6-ba33-4545a70b96bf
DOI: 10.21203/rs.3.rs-6972761/v1

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