Article
Production and Purification of A Cell-Penetrating Peptide-Erythropoietin Fusion Protein and Optimization of an in Vitro Blood-Brain Barrier Model for Central Nervous System Drug Delivery
2020-10-06
Abstract excerpt
<title>Abstract</title> <p>Drug delivery into the central nervous system (CNS) is a brilliant research field, and the development of protein production and purification procedures for novel therapeutic proteins is crucial. Erythropoietin (EPO) is a glycoprotein with tremendous neuroprotective potential, but its bulky size prevents easy penetration across the blood-brain barrier (BBB). EPO-HBHAc is a promising cel...
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Identifiers and source
- Literature Corpus work
- 0f095640-734d-543d-901d-c0ca0125ac5e
- DOI
- 10.21203/rs.3.rs-78080/v1
