Article

Engineering synthetic signaling receptors to enable erythropoietin-free erythropoiesis

2024-10-24

Abstract excerpt

<title>Abstract</title> <p>Blood transfusion plays a vital role in modern medicine. However, availability is contingent on donated blood, and frequent shortages pose a significant healthcare challenge. Ex vivo manufacturing of red blood cells (RBCs) derived from universal donor O-negative pluripotent stem cells emerges as a solution, yet the high cost of recombinant cytokines required for ex vivo erythroid differ...

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Literature Corpus work: 03025e72-20cb-51ba-9132-33ab8bd89e68
DOI: 10.21203/rs.3.rs-4986623/v1

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