Article

Engineering inducible signaling receptors to enable erythropoietin-free erythropoiesis

2024-04-16

Abstract excerpt

<title>Abstract</title> <p>Blood transfusion plays a vital role in modern medicine. However, availability is contingent on donated blood, and frequent shortages pose a significant healthcare challenge. <italic>Ex vivo </italic>manufacturing of red blood cells (RBCs) derived from universal donor O-negative pluripotent stem cells emerges as a solution, yet the high cost of recombinant cytokines required for <italic...

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Literature Corpus work: b13ce1a0-1fd8-587b-b8d6-5f11fc8bbd0b
DOI: 10.21203/rs.3.rs-4259044/v1

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