Article

Genome-wide survey of parent-of-origin specific associations across clinical traits derived from electronic health records

2020-12-11

Abstract excerpt

Parent-of-origin (PoO) effects refer to the differential phenotypic impact of genetic variants dependent on their parental inheritance. Genetic variants in imprinted genes can have PoO specific effects on complex traits, but these effects may be poorly captured by models that do not differentiate the parental origin of the variant. The aim of this study was to screen genome-wide imputed sequence for PoO effects on...

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Literature Corpus work: 610b858d-446f-51fa-b59a-ea802e84458f
DOI: 10.1101/2020.12.08.20246199

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