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Article

Searching for parent-of-origin effects on cardiometabolic traits in imprinted genomic regions.

European journal of human genetics : EJHG - 1 May 2020

Granot-Hershkovitz Einat, Wu Peitao, Karasik David, Peter Inga, Peloso Gina M, Levy Daniel, Vasan Ramachandran S, Adrienne Cupples L, Liu Ching-Ti, Meigs James B, Siscovick David S, Dupuis Josée, Friedlander Yechiel, Hochner Hagit

Abstract excerpt

Cardiometabolic traits pose a major global public health burden. Large-scale genome-wide association studies (GWAS) have identified multiple loci accounting for up to 30% of the genetic variance in complex traits such as cardiometabolic traits. However, the contribution of parent-of-origin effects (POEs) to complex traits has been largely ignored in GWAS. Family-based studies enable the assessment of POEs in...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 31896779
DOI: 10.1038/s41431-019-0568-1
PMCID: PMC7170899

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RCBTB2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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