Article

Abundant Parent-of-origin Effect eQTL: The Framingham Heart Study

2024-06-10

Abstract excerpt

Parent-of-origin effect (POE) is a phenomenon whereby an allele’s effect on a phenotype depends both on its allelic identity and parent’s gender from whom the allele is inherited, as exemplified by the polar overdominance in the ovine callypyge locus and the human obesity DLK1 locus. Systematic studies of POE of expression quantitative trait loci (eQTL) are lacking. In this study we use trios among participants i...

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Literature Corpus work: c28b121a-6ff7-5660-8265-908dc0e9efe8
DOI: 10.1101/2024.06.05.597677

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